Theoklis Zaoutis is Professor of Pediatrics and Epidemiology at the Perelman School of Medicine, and Director of the Graduate Clinical Epidemiology Program at Pennsylvania University (UPENN). He is also Chief of the Department of Infectious Diseases at Philadelphia Pediatric Hospital (CHOP). He has published more than 230 articles in leading international journals. The goal of Professor Zaouti from the post of director of the Center for Pediatric Clinical Effectiveness (CPCE) is the discovery, dissemination, and the implementation of the best practices for more effective care of hospitalized children. He also participates in many advisory committees in the United States and in Europe, such as the Centers for Disease Control and Prevention (CDC), the National Institute of Health (NIH), the American Academy of Pediatrics, and the European Society for Pediatric Infectious Diseases. He has recently been selected as a member of the “Presidential Advisory Committee on the Treatment of An This talk was given at a TEDx event using the TED conference format but independently organized by a local community.